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A late goal restored the lead for AC Milan to take a victory over Rijeka
Arsenal showed their class away at BATE Borisov
| Group A | |||
| Team | Pld | Pts | |
| 1 | Villarreal | 2 | 4 |
| 2 | Slavia Prague | 2 | 4 |
| 3 | Maccabi Tel Aviv | 2 | 1 |
| 4 | Astana | 2 | 1 |
| Group B | |||
| Team | Pld | Pts | |
| 1 | Dynamo Kyiv | 2 | 6 |
| 2 | Young Boys | 2 | 2 |
| 3 | Partizan | 2 | 1 |
| 4 | Skënderbeu Korçë | 2 | 1 |
| Group C | |||
| Team | Pld | Pts | |
| 1 | Braga | 2 | 6 |
| 2 | Ludogorets Razgrad | 2 | 4 |
| 3 | İstanbul Başakşehir | 2 | 1 |
| 4 | 1899 Hoffenheim | 2 | 0 |
| Group D | |||
| Team | Pld | Pts | |
| 1 | Milan | 2 | 6 |
| 2 | AEK Athens | 2 | 4 |
| 3 | Austria Wien | 2 | 1 |
| 4 | Rijeka | 2 | 0 |
| Group E | |||
| Team | Pld | Pts | |
| 1 | Atalanta | 2 | 4 |
| 2 | Lyon | 2 | 2 |
| 3 | Apollon Limassol | 2 | 2 |
| 4 | Everton | 2 | 1 |
| Group F | |||
| Team | Pld | Pts | |
| 1 | Lokomotiv Moscow | 2 | 4 |
| 2 | Copenhagen | 2 | 2 |
| 3 | Sheriff Tiraspol | 2 | 2 |
| 4 | Fastav Zlín | 2 | 1 |
| Group G | |||
| Team | Pld | Pts | |
| 1 | Steaua București | 2 | 6 |
| 2 | Viktoria Plzeň | 2 | 3 |
| 3 | Hapoel Be’er Sheva | 2 | 3 |
| 4 | Lugano | 2 | 0 |
| Group H | |||
| Team | Pld | Pts | |
| 1 | Arsenal | 2 | 6 |
| 2 | Red Star Belgrade | 2 | 4 |
| 3 | BATE Borisov | 2 | 1 |
| 4 | 1. FC Köln | 2 | 0 |
| Group I | |||
| Team | Pld | Pts | |
| 1 | Red Bull Salzburg | 2 | 4 |
| 2 | Marseille | 2 | 3 |
| 3 | Konyaspor | 2 | 3 |
| 4 | Vitória de Guimarães | 2 | 1 |
| Group J | |||
| Team | Pld | Pts | |
| 1 | Östersund | 2 | 6 |
| 2 | Zorya Luhansk | 2 | 3 |
| 3 | Athletic Bilbao | 2 | 1 |
| 4 | Hertha BSC | 2 | 1 |
| Group K | |||
| Team | Pld | Pts | |
| 1 | Nice | 2 | 6 |
| 2 | Lazio | 2 | 6 |
| 3 | Vitesse | 2 | 0 |
| 4 | Zulte Waregem | 2 | 0 |
| Group L | |||
| Team | Pld | Pts | |
| 1 | Zenit Saint Petersburg | 2 | 6 |
| 2 | Real Sociedad | 2 | 3 |
| 3 | Rosenborg | 2 | 3 |
| 4 | Vardar | 2 | 0 |
